Itoh Group Literature Review

Matthew R. Berwick, a Louise N. Slope, a Caitlin F. Smith, a Siobhan M. King, a Sarah L. Newton, a Richard B. Gillis, bc Gary G. Adams, bc Arthur J. Rowe, b Stephen E. Harding, b Melanie M. Britton a and Anna F. A. Peacock * a Chem. Sci. , 2016, Advance Article Received 28th October 2015 Accepted 22nd December 2015 DOI: 10.1039/c5sc04101e  http://pubs.rsc.org/en/Content/ArticleLanding/2016/SC/C5SC04101E#!divAbstract Herein, we establish for the first time the design principles for lanthanide coordination within coiled coils, and the important consequences of binding site translation. By interrogating design requirements and by systematically translating binding site residues, one can influence coiled coil stability and more importantly, the lanthanide coordination chemistry. A 10 Å binding site translation along a coiled coil, transforms a coordinatively saturated Tb(Asp) 3 (Asn) 3  site into one in which three exogenous water molecules...

Anamitra Chatterjee ,   Hendrik Mallin ,   Juliane Klehr ,   Jaicy vallapurackal ,   Aaron Finke ,   Laura Vera ,   ...

Zheng Huang ,   Mohammad S Askari ,   Kenneth Virgel N. Esguerra ,   Tian-Yang Dai ,   Ohhyeon Kwon ,   Xavier Ottenwaelder  and   ...

Farrukh Vohidov, a Sarah E. Knudsen, a Paul G. Leonard, b Jun Ohata, a Michael J. Wheadon, a Brian V. Popp, c John E. Ladbury d and Zachary T. Ball * a a Department of Chemistry, Rice University, 6100 Main St., Houston, Texas, USA. E-mail: zb1@rice.edu b Department of Genomic Medicine, Core for Biomolecular Structure and Function, University of Texas, M.D. Anderson Cancer Center, Houston, Texas, USA c Eugene Bennett Department of Chemistry, West Virginia University, 217 Clark Hall, Morgantown, West Virginia, USA d Department of Molecular and Cellular Biology, University of Leeds, LS2 9JT, UK Chem. Sci., 2015, 6, 4778-4783 Received 2nd May 2015 Accepted 3rd June 2015 DOI: 10.1039/c5sc01602a  http://pubs.rsc.org/en/content/articlelanding/2015/sc/c5sc01602a?iscitedby=True#!divAbstract Abstract Src-family kinases (SFKs) play important roles in human biology and are key drug targets as well. However, achieving selective inhibition of i...

HNO、システインのセンサーとなる化合物の論文です。フルオレセインを発光部位、銅錯体をセンサー部位とし、ペプチド合成の手法を利用してそれらを複合化しています。 Andrei Loas , a      Robert J. Radford , a      Alexandria Deliz Liang a  and   Stephen J. Lippard * a    Show Affiliations Chem. Sci. , 2015, Advance Article DOI:  10.1039/C5SC00880H Received 10 Mar 2015, Accepted 05 May 2015 First published online 19 May 2015 This article is licensed under a  Creative Commons Attribution-NonCommercial 3.0 Unported Licence. |  | Share on citeulike | Share on facebook | Share on twitter | |  More Open Access Learn more.. PDF Rich HTML    Send PDF to Kindle Download Citation BibTex   EndNote   MEDLINE   ProCite   ReferenceManager   RefWorks   RIS   Request Permissions Abstract Cited by Related Content   We describe a modular, synthetically facile solid-phase approa...

藤枝先生、ご遊学中のお仕事です。 RSC - Chem. Sci. latest articles  by Nobutaka Fujieda  /   26d   //   keep unread   //   hide   //   preview Chem. Sci. , 2015, Advance Article DOI : 10.1039/C5SC01065A, Edge Article Open Access &nbsp This article is licensed under a  Creative Commons Attribution 3.0 Unported Licence. Nobutaka Fujieda, Jonas Schatti, Edward Stuttfeld, Kei Ohkubo, Timm Maier, Shunichi Fukuzumi, Thomas R. Ward Adding a metal cofactor to a protein bearing a latent metal binding site endows the macromolecule with nascent catalytic activity. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry Visit Website

Edge Article  Significant improvement of oxidase activity through the genetic incorporation of a redox-active unnatural amino acid Yang Yu , c      Qing Zhou , b      Li Wang , a b      Xiaohong Liu , b      Wei Zhang , b    Meirong Hu , b      Jianshu Dong , b      Jiasong Li , a b      Xiaoxuan Lv , b    Hanlin Ouyang , c      Han Li , b      Feng Gao , b      Weimin Gong , b    Yi Lu * c  and     Jiangyun Wang * b    Show Affiliations Chem. Sci. , 2015, Advance Article DOI:  10.1039/C5SC01126D Received 29 Mar 2015, Accepted 13 Apr 2015 First published online 13 Apr 2015 While nature employs various covalent and non-covalent strategies to modulate tyrosine (Y) redox potential and p K a  in order to optimize enzyme activities, such approaches...

William M. Hart-Cooper , a      Chen Zhao , a      Rebecca M. Triano , a    Parastou Yaghoubi , a      Haxel Lionel Ozores , a      Kristen N. Burford , a    F. Dean Toste , * a      Robert G. Bergman * a  and   Kenneth N. Raymond * a    Show Affiliations Chem. Sci. , 2015, Advance Article DOI:  10.1039/C4SC02735C Received 05 Sep 2014, Accepted 18 Nov 2014 First published online 28 Nov 2014 The effect of host structure on the selectivity and mechanism of intramolecular Prins reactions is evaluated using K 12 Ga 4 L 6  tetrahedral catalysts. The host structure was varied by modifying the structure of the chelating moieties and the size of the aromatic spacers. While variation in chelator substituents was generally observed to affect changes in rate but not selectivity, changing the host spacer afforded differences in efficiency and product d...

RSC - Chem. Sci. latest articles  by Elliott B. Hulley  /   6d   //   keep unread   //   hide   //   preview   +TAG Chem. Sci. , 2014, Advance Article DOI : 10.1039/C4SC01801J, Edge Article Elliott B. Hulley, Monte L. Helm, R. Morris Bullock A balance of metal electrophilicity and ligand steric influences is required for facile, reversible H-H heterolytic cleavage in Mn complexes with pendant amines. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry Visit Website

Edge Article An in-depth understanding of the self-assembly process at the molecular level is crucial in both biological and materials science fields. However, such research is scarce due to the difficulty in monitoring a great deal of fragmentary species that are transiently produced in the process. We present a novel method for investigating the self-assembly process of supramolecular coordination assemblies by following the time variation of the average composition of the fragmentary species, which was indirectly determined by spectroscopy. With this method, we found that the final stage is the rate-determining step of the self-assembly of an octahedron-shaped coordination capsule, and that the relative energy barrier of each step is controllable by modifying the chemical structure of the building blocks.

Andrea Brugnara ,     Filip Topić ,     Kari Rissanen ,   Aurélien de la Lande ,     Benoit Colasson  and     Olivia Reinaud    Chem. Sci. , 2014, Accepted Manuscript DOI:  10.1039/C4SC01457J Received 18 May 2014, Accepted 18 Jun 2014 First published online 18 Jun 2014 | | Share on citeulike | Share on facebook | Share on twitter | | More PDF Rich HTML    Send PDF to Kindle Download Citation BibTex   EndNote   MEDLINE   ProCite   ReferenceManager   RefWorks   RIS   Request Permissions Abstract Cited by Related Content   The ability of a water-soluble pentacationic calix[6]arene-based CuII complex to bind anions in water has been explored. Quite remarkably, the complex exhibits strong and selective fluoride binding in the [6-7] pH range. The binding constant at pH 5.9 was eva...