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REQUIMTE/CQFB, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal
Chem. Rev., Article ASAP
DOI: 10.1021/cr400518y
Publication Date (Web): April 2, 2014
Copyright © 2014 American Chemical Society
*E-mail: jose.moura@fct.unl.pt.
- 1. Introduction
- 2. Biological Fate of Nitrite
- 2.1. Biological Fate of Nitrite – Nitrite in the Nitrogen Cycle
- 2.1.1. Classic and New Pathways
- 2.1.2. Nitrite and Nitrogen “Recycling”
- 2.2. Biological Fate of Nitrite – Nitrite in Signaling Pathways
- 2.2.1. Nitrite in Signaling Pathways in Mammals
- 2.2.2. Nitrite in Signaling (and Other) Pathways in Plants
- 2.2.3. Nitrite in Signaling (and Other) Pathways in Bacteria
- 2.1. Biological Fate of Nitrite – Nitrite in the Nitrogen Cycle
- 3. Biological Mechanistic Strategies To Handle Nitrite
- 3.1. Nitrite Reduction to Ammonium
- 3.1.1. Dissimilatory Nitrite Reduction to Ammonium
- 3.1.2. Assimilatory Nitrite Reduction to Ammonium
- 3.1.3. Nitrite Reduction to Ammonium by Other Enzymes
- 3.2. Nitrite Reduction to Nitric Oxide
- 3.2.1. Dissimilatory Nitrite Reduction to Nitric Oxide by an Iron-Dependent Enzyme
- 3.2.2. Dissimilatory Nitrite Reduction to Nitric Oxide by a Copper-Dependent Enzyme
- 3.2.3. Signaling Nitrite Reduction to Nitric Oxide by a Molybdenum-Dependent Enzyme
- 3.3. Nitrite Oxidation to Nitrate
- 3.3.1. Dissimilatory Nitrite Oxidation to Nitrate
- 3.1. Nitrite Reduction to Ammonium
- 4. Outlook
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